Deflazacort Tablets

Deflazacort, alsoknown as Emflaza, is a corticosteroid pro-drug that is used as an agent to manage Duchenne Muscular Dystrophy (DMD) disease. This drug is marketed by Marathon Pharmaceuticals and was approved in 2017 by the Federal Drug Assoiation (FDA). Duchenne Muscular Dystrophy is an inherited disorder resulting from mutations of the dystrophin gene, which is important for muscle function. This DMD can cause serious muscle weakness and progressive breathing and cardiovascular disability, which can result in severely impacting patient quality of life and survival.

The sign of DMD usually manifests by muscle weakness in early childhood, which is followed by loss of the ability to walk in the formative years. Deflazacort works upon DMD and helps delay the onset of muscle related complications. This would help in prolonging the lives of children diagnosed with DMD. At the same time, Deflazacort causes less harmful effects on the bone health and weight than other steroid medications.

Deflazacort belongs to a class of medicines known as corticosteroids or just oral steroids. Deflazacort is a synthetic glucocorticoid pro-medicine that carries anti-inflammatory and immune-modulating properties. When this medicine is taken, the active metabolite of deflazacort binds to and activates tissue glucocorticoid receptors. This results in the inhibition of specific leukocyte functions and the inhibition of pro-inflammatory cytokine production. Deflazacort are used to treat a wide variety of conditions such as autoimmune diseases, for example, systemic lupus erythematosus (SLE), autoimmune hepatitis, sarcoidosis, joint and muscle diseases like rheumatoid arthritis, allergies and asthma.

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