Diclazuril - 2,6-dichloro-a-(4-chlorophenyl)-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3h)-yl) Benzeneacetonitrile, Indicated For Anticoccidial Use In Poultry And Edible Bird Species

Diclazuril is an anticoccidial drug used in major poultry species, such as broiler chickens, replacement pullets and turkeys, as well as in rabbits, lambs and minor edible bird species.
The chemical name of the compound is: 2,6-dichloro-a-(4-chlorophenyl)-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl) benzeneacetonitrile.

In all species investigated, there were little indications of metabolism of diclazuril. As a result, diclazuril-derived substances were eliminated mainly as unchanged parent substance in the excreta of bird species, and in the faeces of rats and rabbits. Urine of the latter species was only a very minor
excretion route and some metabolized substances could be observed. In edible tissues, the residues consisted almost entirely of unchanged diclazuril.