Diclofenac Potassium Powder Cas No: 15307-81-0

TESTSSPECIFICATIONSRESULTS
DescriptionA White or slight yellowish, slightly hygroscopic Crystalline powderwhite crystalline powder
SolubilitySparingly soluble in water and freely soluble in Methanol, Soluble in Ethanol (96%), Slightly soluble in acetone.Complies
Identification (First Identification A, D & Second identification B, C, D)
By IRThe infrared spectrum of diclofenac Potassium in sample, should concordant with the reference spectrum of diclofenac Potassium or with the spectrum obtained from diclofenac Potassium working standardComplies

BY TLCThe principal spot in the chromatogram obtained with the test solution is shall be similar in position and size to the principal spot in the chromatogram obtained with reference SolutionComplies

Chemical TestA blue colour develops and a precipitate is formedComplies

Reaction Of PotassiumA yellow or orange a yellow precipitate is formed immediately.Complies
Appearance of solutionThe solution shall be clear and absorbance at 440 nm is not greater than 0.05Complies
Related Substance (By HPLC)Impurity A - Not more than 0.15%0.055%
Impurity F - Not more than 0.15%0.033%
Unspecified Impurities a Not more than 0.1%0.069%
Total Impurities a Not more than 0.4%0.219%
Loss on drying (%w/w)
At 105au C for 3hNot more than 0.5%0.30%
Assay (%w/w)99.00 per cent to 101.0 per cent (dried substances)99.98%