Medicine Raw Materials Ondansetron Ip/bp/usp/ep

Niksan Pharmaceutical is one of the leading manufacturer, supplier and exporter of the Ondansetron. The best product manufactured by Niksan Pharmaceutical is Ondansetron. We manufacture, supply and export best quality product of Ondansetron API along with Ondansetron formulations.
Niksan Pharmaceutical is the largest manufacturer, trader and supply of Ondansetron in all-over Ankleshwar, Gujarat, India.
Niksan Pharmaceutical manufacture and supply the Ondansetron product to the Indian states like Maharashtra, Goa, Sikkim, Madhya Pradesh, Uttar Pradesh, Assam, Haryana, Delhi, Bihar, Meghalaya, Tamilnadu, Kerala, Gujarat, Rajasthan, Rajasthan, Punjab,Karnataka, and other states.
Niksan Pharmaceutical is manufacturer , supplier and exporter of Ondansetron in many countries from many years like New Zealand, United States, Paraguay, Indonesia, Mexico, Australia, Chile, Nepal, Venezuela, Ecuador, Puerto Rico, Colombia, Uruguay, Kenya, Bolivia, Canada, Peru, Bangladesh, Portugal, Ireland, United Kingdom, Iraq, United Arab Emirates, Singapore, Sweden, Iran, Pakistan, Spain, Argentina, Philippines, Saudi Arabia, Finland, Denmark, Switzerland, Netherlands, Germany, South Africa, Thailand, Egypt, Austria, Malaysia, Italy, Belgium, France, Poland, Vietnam, Turkey, Brazil and many more countries.

Ondansetron belongs to 5-HT3 antagonist class of medicine. Ondansetron used as an anti-emetic agent to prevent nausea and vomiting caused by the cancer therapy. It is also used to prevent vomiting caused by motion sickness.
IUPAC NAME: 9-methyl-3-[(2-methyl-1H-imidazol-1-yl) methyl]-2, 3, 4, 9-tetrahydro-1H-carbazol-4-one
CAS NO: 99614-02-5
FORMULA: C18H19N3O
MOLECULAR MASS: 293.4 g/mol
STORAGE CONDITIONS: Store in cool and dry place, away from heat and light. Do not put in bathroom or ant misty place. Keep away from children.

HOW TO USE: This medication come in mouth dissolving formulation, so do not chew or break the medicine. Place medicine on the tip of the tongue and allow dissolving it. Swallow the medicine after dissolves in the mouth.

HOW ONDANSETRON WORKS: Ondansetron used as anti-emetic agent. Ondansetron blocks the action of 5-HT3 receptor which causes the nausea and vomiting symptoms.

PHARMACOKINETICS: Ondansetron absorbed in GI after the oral administration. Almost 73% drug binds with the plasma protein. The half life of Ondansetron is 3-4 hours. Ondansetron eliminated from body by urination and feces.

SIDE EFFECTS: Side effects cause by Ondansetron is dizziness, light headedness, drowsiness, headache, tiredness. Other side effects like chest pain, irregular heartbeats, fainting, and abdominal pain. Muscle pain seen in the patients.

PRECAUTIONS: Before taking the medication tell your doctor if you are allergic towards the medicine. The medicine makes you dizzy so kindly avoid drinking alcohol and cannabis. This drug makes you dizzy so kindly avoid driving or operating machineries.

CDSCO APPROVAL: R-Ondansetron (As HCl. Dihydrate) (1mg/ml) injection approved by CDSCO in India in 12.01.2007,
Ondansetron Fast Dissolving Strips 4mg/8mg (New dosage form) approved by CDSCO in India in22.11.2011
Ondansetron orally disintegrating tablet (4mg/8mg) (additional dosage form)approved by CDSCO in India in 10.10.2007
Ondansetron tablet and injection approved by CDSCO in India in12.02.1994
Ondansetron Rapid Film Oral Strip 4/8 mg approved by CDSCO in India in16.11.2010
Ondansetron Hydrochloride Mouth Melting Strips 4mg approved by CDSCO in India in29.03.2012
R (+) Ondansetron (2mg/4mg) tablet approved by CDSCO in India in15.04.2005
Ondansetron Hydrochloride Oral Spray 2mg (Each spray delivers ondansetron-2mg)approved by CDSCO in India in 08.11.2012
R (-) Ondansetron oral Solution (1mg/5ml) approved by CDSCO in India in27.05.2005

FORMULATIONS AVAILABLE IN MARKET:
Ondansetron Fast Dissolving Strips 4mg
Ondansetron Fast Dissolving Strips 8mg
Ondansetron 4mg orally disintegrating tablets
Ondansetron 8mgorally disintegrating tablets
Ondansetron injections
Ondansetron Rapid Film Oral Strips 4mg
Ondansetron Rapid Film Oral Strips 8mg
R (+) Ondansetron 2mg tablets
R (+) Ondansetron 4mg tablets
R (-) Ondansetron 1mg/5ml oral Solution

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk.

REFERENCES:

www.webmd.com
https://pubchem.ncbi.nlm.nih.gov
https://go.drugbank.com
https://cdscoonline.gov.in
https://www.wikipedia.org/
https://www.drugs.com
https://www.zaubacorp.com
https://www.practo.com/consult